Public and global health examines how we protect communities from disease, manage outbreaks, and improve well-being across the world. This vital field connects diverse research on everything from infectious disease control and vaccination strategies to the social factors that shape our collective health. Because these studies often impact policy and daily life, understanding them quickly is more important than ever.

At Gist.Science, we track every new preprint published in this category on medRxiv to ensure you never miss a breakthrough. We process each submission to provide both plain-language explanations for general readers and detailed technical summaries for experts, making complex findings accessible to everyone.

Below are the latest papers in public and global health, freshly summarized from the most recent medRxiv releases.

Enhanced Insights into Alcohol Use Disorder from Lifestyle, Background, and Family History in a Large-Scale Machine Learning Study

This study leverages an expanded All of Us Research Program dataset and machine learning to confirm that annual income, family history, and various lifestyle factors are robust, multi-level determinants of Alcohol Use Disorder, with Random Forest models achieving 81% accuracy in predicting AUD status.

Wang, C., Luo, Y., Huang, G., Zhou, W.2026-03-03📄 public and global health

Large Language Models Readability Classification: A Variability Analysis of Sources and Metrics

This study reveals that while Large Language Models produce homogeneous readability at baseline, their output complexity becomes significantly variable when grounded in external sources like Wikipedia, and that readability metrics are not interchangeable, necessitating transparent, metric-specific, and language-aware evaluation protocols for accessible health communication.

Corrale de Matos, H. G., Wasmann, J.-W. A., Catalani Morata, T., de Freitas Alvarenga, K., Bornia Jacob, L. C.2026-03-02📄 public and global health

The long-term impact and effectiveness of rotavirus vaccination in Malawi: an interrupted time-series and case-control analysis

This study demonstrates that the monovalent rotavirus vaccine (Rotarix) in Malawi provided moderate, age-dependent protection against hospitalisation for diarrhoea over seven years, with significant impact limited to infants and no measurable influence from the concurrent switch from trivalent to bivalent oral poliovirus vaccine.

Ndeketa, L., Pitzer, V. E., Jere, K. C., Bennett, A., Cunliffe, N. C., Dodd, P. J., French, N., Hungerford, D.2026-03-02📄 public and global health

The association between the Ages and Stages Questionnaire 3 assessment at age 2 and the Early Years Foundation Stage at age 5: A longitudinal observational study using routine data

This longitudinal study of 47,046 children in England reveals that achieving a Good Level of Development on the Ages and Stages Questionnaire-3 at age two is a strong predictor of similar success on the Early Years Foundation Stage Profile at age five, highlighting the critical need for early intervention to address developmental inequities among boys, children in deprived areas, and specific ethnic groups.

Dickerson, J., Xu, Y., Shore, R., Henderson, H., Lee, D., Bennett, K., Degnan, P., Sohal, K., Mon-Williams, M., Wright, J., Mooney, K. E.2026-03-02📄 public and global health

Antimicrobial resistance prevalence in clinical and aquatic environmental ESKAPE: a systematic review with meta-analysis

This systematic review and meta-analysis reveals that while antimicrobial resistance in ESKAPE pathogens is significantly more prevalent in clinical isolates than in aquatic environments, wastewater and effluent-impacted waters serve as critical reservoirs of resistance, highlighting the need for standardized methodologies within a One Health framework.

Vaz, A. B. M., Murad, B., Lopes, B. C., Castro, M. L. P., Fernandes, G. R., Oliveira, W. K., Fonseca, P. L. C., Aguiar, E. R. G. R., Mota Filho, C. R., Santos, A. B., Starling, C. E. F.2026-02-28📄 public and global health

High-Resolution District Level Contraceptive Prevalence in Pakistan Using a Bayesian Small Area Estimation Approach

This study employs a two-stage Bayesian small area estimation framework that integrates routine commodity data, census figures, and national survey benchmarks to generate high-resolution, statistically robust district-level estimates of contraceptive prevalence in Pakistan, thereby addressing data gaps and enabling more targeted family planning interventions.

Ibrahim, M., Naz, O., Javeed, A., Irum, A., Khan, A., Khan, A. A.2026-02-28📄 public and global health

EXPLORING CLINICIANS PERSPECTIVES TOWARDS AI-RADIOLOGY & ITS CLINICAL ADOPTION: A QUALITATIVE STUDY FROM PAKISTAN

This qualitative study of 13 clinicians in Karachi, Pakistan, reveals that while AI in radiology is viewed as a promising assistant for specific tasks like screening and workload reduction, its successful adoption in this low-resource setting depends on addressing infrastructure gaps, ensuring data privacy, providing targeted training, and maintaining human oversight through strategic, staged implementation.

Bismillah, I., Tikmani, S. S., Afzal, S., Naz, N., Vohra, L. B.2026-02-28📄 public and global health

The Prevalence, Prevention, and Treatment of Cardiovascular Diseases in Twelve African Countries (2014-2019): An Analysis of the World Health Organisation STEPwise Approach to Chronic Disease Risk Factor Surveillance

This study analyzed WHO STEPS data from twelve African countries between 2014 and 2019, revealing a 5% prevalence of cardiovascular diseases and critically low rates of prevention and treatment uptake, thereby highlighting an urgent need to improve diagnosis and expand care to reduce premature deaths.

Ng'ambi, W. F., Estill, J., Merzouki, F. A., Zyambo, C., Chiwanda, J., Beran, D., Keiser, O.2026-02-27📄 public and global health